Maxwell Enterprises

�� Valcivir 1000 mg Tablet

• Generic Name: Valacyclovir Hydrochloride

• Brand Name: Valcivir

• Strength: 1000 mg

• Manufacturer: Cipla Ltd

• Drug Class: Antiviral (Nucleoside analogue)

�� Composition:

Each tablet contains:

• Valacyclovir Hydrochloride 1000 mg (prodrug of acyclovir)

�� Indications (Uses):

Valcivir 1000 mg is prescribed for:

1. Herpes Zoster (Shingles)

2. Genital Herpes (initial & recurrent episodes)

3. Cold Sores (Herpes Labialis)

4. Suppression of recurrent genital herpes

5. Reduction of transmission of genital herpes

6. Cytomegalovirus (CMV) prophylaxis in transplant patients

7. Chickenpox (in immunocompromised adults in some cases)

⚙️ Mechanism of Action:

Valacyclovir is rapidly converted to Acyclovir in the body. Acyclovir acts by:

• Inhibiting viral DNA polymerase

• Incorporating into viral DNA and terminating its synthesis
  This stops the replication of herpes viruses.

�� Dosage & Administration:

• Shingles (Herpes Zoster): 1000 mg 3 times daily for 7 days

• Genital Herpes (initial): 1000 mg twice daily for 7–10 days

• Recurrent episodes: 500 mg twice daily for 3 days

• Suppression: 500–1000 mg once daily

• CMV Prophylaxis: 2000 mg 4 times daily (adjusted by condition)

Note: Dose adjustment needed in renal impairment

��️ Shelf Life: 24–36 months �� Storage: Store below 30°C, protect from moisture �� Key Points:

• Valcivir is more bioavailable than plain acyclovir → requires less frequent dosing

• Used early in the outbreak for better results

• Effective in reducing viral shedding and transmission risk in long-term use

 

Additional Information:

• Delivery Time: 12-15 days

💊 Atazor 200 mg Capsule

Generic Name: Atazanavir 200 mg
Manufacturer: Emcure Pharmaceuticals Ltd
Drug Class: Protease Inhibitor (Antiretroviral)
Indication:

• Used in the treatment of HIV-1 infection, typically in combination with other antiretroviral agents.

• Helps reduce the viral load and boost immune function.

Mechanism of Action:

• Inhibits the HIV-1 protease enzyme, which is essential for viral replication. Prevents cleavage of gag-pol polyproteins, resulting in immature, noninfectious virus particles.

Dosage & Use:

• Typically given as two 200 mg capsules once daily with Ritonavir 100 mg.

• Must be taken with food to improve absorption.

Side Effects:

• Jaundice, nausea, hyperbilirubinemia, rash, abdominal pain, lipid changes.

Shelf Life:

• Usually 24 months from the date of manufacture.

💊 Atazor 300 mg Capsule

Generic Name: Atazanavir 300 mg
Manufacturer: Emcure Pharmaceuticals Ltd
Drug Class: Protease Inhibitor (Antiretroviral)
Indication:

• First-line and widely used drug for HIV-1 treatment in combination with Ritonavir or Cobicistat, and a dual NRTI backbone.

Mechanism of Action:

• Same as above – inhibits HIV protease, blocking viral replication.

Dosage & Use:

• One capsule (300 mg) once daily with Ritonavir 100 mg, along with other antiretrovirals.

• Must be taken with food.

Side Effects:

• Similar to 200 mg, with more pronounced bilirubin elevation in some patients due to higher plasma concentrations.

Shelf Life:

• Also 24 months from manufacture date.

Additional Information:

• Delivery Time: 12-15 days

💊 Atazor-R Capsule

Manufacturer: Emcure Pharmaceuticals
Composition:

• Atazanavir 300 mg

• Ritonavir 100 mg

Description:
Atazor-R is a fixed-dose combination of two antiretroviral agents:

• Atazanavir, a protease inhibitor, suppresses HIV replication by inhibiting the viral protease enzyme.

• Ritonavir acts as a pharmacokinetic enhancer, increasing the effectiveness of atazanavir by inhibiting its metabolism.

Indication:
Used in combination with other antiretrovirals for the treatment of HIV-1 infection in adults and adolescents.

Dosage:
Usually once daily with food, as prescribed by a healthcare provider.

Shelf Life:
24 months from the date of manufacture.

💊 Hiataz-R Capsule

Manufacturer: Hetero Healthcare
Composition:

• Atazanavir 300 mg

• Ritonavir 100 mg

Description:
Hiataz-R is another fixed-dose combination antiretroviral therapy. It contains the same active ingredients as Atazor-R and works similarly:

• Suppresses the HIV viral load.

• Increases CD4 cell count.

• Slows disease progression when used as part of a triple-drug regimen.

Indication:
Approved for the management of HIV-1 infection in combination therapy.

Dosage:
Typically once daily with food.

Shelf Life:
24 months from manufacturing.

Additional Information:

• Delivery Time: 12-15 days

💊 Virem 600 mg Tablet

Manufacturer: Emcure Pharmaceuticals
Generic Name: Efavirenz 600 mg

📄 Description:

Virem 600 mg contains Efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretroviral agents for the treatment of HIV-1 infection.

Efavirenz works by inhibiting reverse transcriptase, an enzyme crucial for the replication of the HIV virus. By doing so, it helps reduce the viral load and increase CD4 cell count, thereby improving immune function.

✅ Indications:

• Part of highly active antiretroviral therapy (HAART) for:

  • HIV-1 infection in adults and children (≥3 years or ≥10 kg)

  • Post-exposure prophylaxis (PEP) in some regimens when combined appropriately

💊 Dosage:

• 600 mg once daily, preferably at bedtime to minimize CNS side effects

• Should be taken on an empty stomach (food increases risk of side effects, especially CNS-related)

⚠️ Warnings & Precautions:

• May cause dizziness, insomnia, vivid dreams, or confusion – typically resolves over time

• Use caution in patients with psychiatric history or liver impairment

• Avoid alcohol and drugs that may increase CNS effects

• Not recommended during pregnancy, unless no alternative available (older concern due to potential teratogenicity)

📦 Shelf Life:

• 24 months from date of manufacture

• Store at room temperature, away from moisture and heat

Additional Information:

• Delivery Time: 12-15 days

💊 Dareit-R Tablet

• Composition: Darunavir 800 mg + Ritonavir 100 mg

• Category: Protease inhibitor combination

• Usage:

  • Used in second-line HIV treatment

  • Prescribed when patients are resistant to first-line antiretrovirals

• Mechanism:

  • Darunavir inhibits the HIV protease enzyme, preventing viral replication.

  • Ritonavir boosts Darunavir's levels by slowing its metabolism.

• Dosage: Once daily (usually with food)

• Common Side Effects: Rash, nausea, abdominal pain, diarrhea, lipid elevation

• Special Note: Must be used in combination with other antiretroviral agents.

💊 Nuace Tablet

• Composition: Tenofovir Disoproxil Fumarate 300 mg + Lamivudine 300 mg + Dolutegravir 50 mg

• Category: Fixed-dose combination antiretroviral therapy

• Usage:

  • First-line treatment of HIV-1 infection in adults and adolescents

  • Aligns with WHO-recommended regimen

• Mechanism:

  • Tenofovir & Lamivudine are nucleoside reverse transcriptase inhibitors (NRTIs)

  • Dolutegravir is an integrase strand transfer inhibitor (INSTI)

• Dosage: Once daily

• Common Side Effects: Headache, insomnia, nausea, fatigue, dizziness

• Advantages: High barrier to resistance, well-tolerated

💊 Virem-R Tablet

• Composition: Tenofovir Disoproxil Fumarate 300 mg + Lamivudine 300 mg + Ritonavir-boosted Dolutegravir 50 mg (or Dolutegravir alone depending on formulation)

• Category: Triple-drug combination ART

• Usage:

  • Widely used for first-line ART in adults and adolescents

  • Suitable for treatment-naïve patients

• Mechanism:

  • Same as Nuace: Combines NRTIs and INSTI for potent viral suppression.

• Dosage: Once daily

• Common Side Effects: Similar to Nuace

• Advantages:

  • Preferred in national HIV treatment programs

  • Effective against resistant strains (Dolutegravir’s benefit)

  • Cost-effective and WHO-aligned

Additional Information:

• Delivery Time: 12-15 days

💊 Xapavir 50 mg

Generic Name: Dolutegravir 50 mg
Manufacturer: Emcure Pharmaceuticals

📌 Description:
Xapavir is an antiretroviral medication containing Dolutegravir, an integrase strand transfer inhibitor (INSTI) used in the treatment of HIV-1 infection. It works by blocking the HIV integrase enzyme, which is essential for viral replication.

🧪 Composition:

• Dolutegravir Sodium equivalent to Dolutegravir 50 mg

💡 Uses:

• HIV-1 infection (usually in combination with other antiretrovirals)

📆 Dosage:

• Typically once daily, as advised by a physician

• May be used once or twice daily depending on previous ART history and resistance profile

⚠️ Side Effects:

• Insomnia

• Headache

• Nausea

• Diarrhea

• Rarely, liver enzyme elevation

💊 Instgra 50 mg

Generic Name: Dolutegravir 50 mg
Manufacturer: Hetero Healthcare

📌 Description:
Instgra is a generic form of Dolutegravir, a potent HIV integrase inhibitor. It helps reduce the amount of virus in the body, keeping the immune system strong and lowering the chances of developing HIV-related complications.

🧪 Composition:

• Dolutegravir Sodium equivalent to Dolutegravir 50 mg

💡 Uses:

• Used in combination ART regimens for the management of HIV-1

📆 Dosage:

• Typically once daily, can be adjusted based on ART regimen

⚠️ Side Effects:

• Fatigue

• Depression (rare)

• Rash

• Gastrointestinal disturbances

✅ Note:
Instgra is widely prescribed due to its high genetic barrier to resistance and convenient dosing.

💊 Myltega

Generic Name: Tenofovir Alafenamide 25 mg + Emtricitabine 200 mg + Dolutegravir 50 mg
Manufacturer: Mylan (Viatris)

📌 Description:
Myltega is a once-daily fixed-dose combination tablet containing three antiretroviral agents:

• Dolutegravir (INSTI)

• Emtricitabine (NRTI)

• Tenofovir Alafenamide (NRTI)
  This combo provides complete HIV-1 therapy in a single pill, improving adherence.

🧪 Composition:

• Dolutegravir 50 mg

• Emtricitabine 200 mg

• Tenofovir Alafenamide (TAF) 25 mg

💡 Uses:

• First-line treatment of HIV-1 infection in adults and adolescents

📆 Dosage:

• One tablet once daily with or without food

⚠️ Side Effects:

• Headache

• Nausea

• Fatigue

• Insomnia

• Possible weight gain with long-term use

✅ Advantages:

• Single-pill regimen

• Low renal and bone toxicity (due to TAF over TDF)

• High potency with minimal resistance

Additional Information:

• Delivery Time: 12-15 days

💊 Efavir 600 mg Tablet

Generic Name: Efavirenz 600 mg
Manufacturer: Cipla Ltd

📌 Description:
Efavir 600 mg is a single-drug non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infection, commonly prescribed as part of a triple drug regimen.
Efavirenz works by blocking the reverse transcriptase enzyme, thereby preventing the virus from multiplying in the body.

It is commonly found in fixed-dose combinations such as TLE (Tenofovir + Lamivudine + Efavirenz).

🧪 Composition:

• Efavirenz 600 mg

💡 Indication / Uses:

• Treatment of HIV-1 infection in adults and adolescents

• Often used as part of first-line therapy (especially prior to Dolutegravir-based regimens)

📆 Dosage:

• One tablet daily, usually at bedtime (to minimize central nervous system side effects)

• Often taken with other ARVs like Tenofovir and Lamivudine

 

✅ Benefits:

• Long-standing usage with well-established efficacy

• Once-daily dosing

• Cost-effective

• Still in use in many national HIV programs (especially where Dolutegravir isn’t available)

🗓️ Shelf Life:

• 24 months from date of manufacture

• Store below 30°C, in original packaging away from moisture

💊 Efcure 200 mg Capsule

Generic Name: Efavirenz 200 mg
Manufacturer: Emcure Pharmaceuticals Ltd

📌 Description:
Efcure 200 mg is a lower-strength Efavirenz formulation, primarily used in pediatric HIV treatment or for dose adjustment in adults when 600 mg tablets are not preferred.
It works via the same mechanism — blocking HIV reverse transcriptase and preventing viral replication.

It may be used as 3 capsules once daily in adults if 600 mg tablets are unavailable.

🧪 Composition:

• Efavirenz 200 mg

💡 Indication / Uses:

• Pediatric HIV-1 therapy (dose adjusted by weight)

• Adults requiring dose-splitting or gradual titration

• Useful in combination regimens where separate drug control is needed

📆 Dosage:

• Adults: 3 capsules once daily = 600 mg

• Children: Dosing by weight (e.g., 10–20 mg/kg/day)

• Always under supervision of a healthcare provider

✅ Benefits:

• Flexibility in dose customization

• Preferred in pediatrics

• Available for programs focusing on children's HIV treatment

🗓️ Shelf Life:

• 24 months

• Store below 30°C, keep dry

Additional Information:

• Delivery Time: 12-15 days

💊 Emduo Kit 30 mg

Manufacturer: Mylan Pharmaceuticals (a Viatris company)
Drug Class: Antiretroviral combination kit
Used For: HIV-1 Infection

📦 Kit Composition:

Each Emduo Kit 30 mg typically contains a daily combination of the following 2 tablets (commonly packed together):

1. Efavirenz 600 mg tablet

2. Lamivudine 300 mg + Tenofovir Disoproxil Fumarate (TDF) 300 mg tablet

🔹 Total Daily Dose:

• Efavirenz 600 mg

• Lamivudine 300 mg

• Tenofovir DF 300 mg

⚠️ This is equivalent to a TLE regimen, but provided as 2 separate pills per day (not a single fixed-dose combination tablet).

📌 Description:

Emduo Kit 30 mg is used for the once-daily treatment of HIV-1 infection in adults and adolescents. It combines three antiretroviral agents that work together to suppress the replication of the virus in the body.

This kit format is useful in areas where fixed-dose combinations like TLE are unavailable, or when individual control over doses is desired.

💡 Mechanism of Action:

• Tenofovir (TDF): A nucleotide reverse transcriptase inhibitor (NRTI)

• Lamivudine: A nucleoside reverse transcriptase inhibitor (NRTI)

• Efavirenz: A non-nucleoside reverse transcriptase inhibitor (NNRTI)

These three drugs block reverse transcriptase — an enzyme HIV needs to replicate.

📆 Dosage & Administration:

• 1 kit daily (containing 2 tablets):

  • Take both tablets together at bedtime, ideally on an empty stomach to reduce CNS side effects from Efavirenz.

✅ Advantages:

• Complete triple-drug therapy in 1 kit

• Good for settings where single-pill TLE is unavailable

• Flexible in dose adjustments if needed

🗓️ Shelf Life:

• 24 months from date of manufacture

• Store below 30°C, keep in a dry place

🔍 Clinical Notes:

• Not recommended as first-line anymore in some countries (due to shift to Dolutegravir-based regimens like TLD)

• Still widely used in many HIV programs

• Effective and affordable therapy for viral load suppression

Additional Information:

• Delivery Time: 12-15 days

💊 1. Lavir 150 mg Tablet

Generic Name: Lamivudine 150 mg
Manufacturer: Cipla Ltd
Class: NRTI – Nucleoside Reverse Transcriptase Inhibitor
Indications:

• HIV-1 infection (as part of ART combination)

• Chronic Hepatitis B (off-label in some cases)

📌 Description:

Lavir 150 mg is a widely used antiretroviral medicine that contains Lamivudine, a key backbone drug in many first-line HIV regimens. It is usually prescribed with Zidovudine, Tenofovir, or Efavirenz.

It inhibits the reverse transcriptase enzyme, thereby preventing HIV from replicating in the body.

💡 Common Uses:

• ART (Antiretroviral Therapy) – used in fixed-dose combinations like TLE, Duovir, etc.

• Sometimes used as a standalone or with Tenofovir in co-infected HIV-HBV patients

🗓️ Shelf Life:

• 36 months from manufacturing

• Store below 30°C, away from moisture

✅ Highlights:

• WHO-approved molecule

• Highly effective, well tolerated

• Foundational drug in HIV programs worldwide

• Cost-effective and broadly available

💊 2. Heptavir 100 mg Tablet

Generic Name: Lamivudine 100 mg
Manufacturer: Hetero Healthcare
Class: NRTI – Nucleoside Reverse Transcriptase Inhibitor
Indications:

• Chronic Hepatitis B virus (HBV) infection

📌 Description:

Heptavir 100 mg is used specifically for the management of chronic Hepatitis B, not HIV. It slows down viral replication and reduces liver inflammation and fibrosis progression.

Though it shares the same molecule (Lamivudine) as Lavir, it comes in a 100 mg dose, which is the standard for HBV monotherapy — not for HIV.

💡 Common Uses:

• Monotherapy for chronic Hepatitis B, especially in resource-limited settings

• Alternative option if Tenofovir is contraindicated

🗓️ Shelf Life:

• 24 to 36 months

• Store at room temperature, under 30°C

✅ Highlights:

• Trusted option for HBV control

• Usually replaced by Tenofovir due to higher HBV resistance with Lamivudine

• Affordable and easy to use

Additional Information:

• Delivery Time: 12-15 days

💊 Nevilast 40 mg Tablet

Manufacturer: Hetero Healthcare Ltd
Type: Fixed-Dose Combination Antiretroviral (Triple Drug)
Drug Class: NRTIs + NNRTI
Formulation: Oral tablet

🧪 Composition (Each tablet contains):

• Stavudine – 40 mg

• Lamivudine – 150 mg

• Nevirapine – 200 mg

This fixed-dose combination is part of the first-generation ART regimens used in the management of HIV-1 infection.

📌 Description:

Nevilast 40 mg is a triple combination antiretroviral tablet that combines:

• Two NRTIs (Stavudine + Lamivudine): They work by mimicking natural nucleosides and blocking reverse transcriptase.

• One NNRTI (Nevirapine): It binds directly to reverse transcriptase and inhibits its function.

Together, they inhibit viral replication and help control the HIV infection, reducing the viral load and improving immune function.

💡 Indications / Uses:

• Treatment of HIV-1 infection in adults and adolescents

• Often prescribed in resource-limited settings

• Used as part of combination ART

🔄 Dosage:

• Typically one tablet twice daily, or as directed by a healthcare provider

• Dosing must be adjusted in case of liver or kidney dysfunction

• Nevirapine requires a lead-in period of 14 days (if starting freshly)

🗓️ Shelf Life:

• 24 to 36 months from manufacturing date

• Store below 30°C, in a cool, dry place

📦 Packaging:

• Typically available in:

  • 30-tablet bottle

  • 10-tablet strip

• Color: Often white or off-white tablets

Additional Information:

• Delivery Time: 12-15 days

💊 Alltera Tablet

• Manufacturer: Hetero Healthcare Ltd

• Formulation: Fixed-dose combination (FDC) tablet

• Drug Class: Antiretroviral Therapy – NRTIs + NNRTI

🧪 Composition (per tablet):

• Tenofovir Disoproxil Fumarate (TDF) – 300 mg

• Lamivudine (3TC) – 300 mg

• Efavirenz (EFV) – 600 mg

📌 Indications:

• Treatment of HIV-1 infection in adults and adolescents

• Recommended as a first-line ART regimen by WHO

• Effective in viral suppression and immune recovery

⚙️ Mechanism of Action:

• Tenofovir and Lamivudine: NRTIs that inhibit reverse transcriptase by causing DNA chain termination

• Efavirenz: NNRTI that binds directly to reverse transcriptase and inhibits viral replication

💡 Dosage & Administration:

• One tablet once daily, preferably at bedtime

• Can be taken with or without food, but taking with food may increase Efavirenz absorption

💊 Emletra Tablet

• Manufacturer: Emcure Pharmaceuticals Ltd

• Formulation: Fixed-dose combination tablet

• Drug Class: NRTIs + NNRTI

🧪 Composition (per tablet):

• Tenofovir Disoproxil Fumarate (TDF) – 300 mg

• Lamivudine (3TC) – 300 mg

• Efavirenz (EFV) – 600 mg

📌 Indications:

• HIV-1 infection treatment in adults and adolescents

• WHO-recommended first-line ART regimen

⚙️ Mechanism of Action:

• Same as Alltera (NRTIs + NNRTI)

💡 Dosage & Administration:

• One tablet once daily at bedtime

• May be taken with or without food

💊 Hivus LR Tablet

• Manufacturer: Hetero Healthcare Ltd

• Formulation: Fixed-dose combination tablet

• Drug Class: NRTIs + NNRTI

🧪 Composition (per tablet):

• Lamivudine (3TC) – 150 mg

• Zidovudine (AZT) – 300 mg

• Efavirenz (EFV) – 600 mg

📌 Indications:

• Treatment of HIV-1 infection

• Alternative regimen especially when Tenofovir is contraindicated or not tolerated

⚙️ Mechanism of Action:

• Zidovudine and Lamivudine inhibit reverse transcriptase (NRTIs)

• Efavirenz inhibits reverse transcriptase (NNRTI)

💡 Dosage & Administration:

• One tablet twice daily or as prescribed

• Food intake not critical, but consistent dosing recommended

💊 Ritocom Tablet

• Manufacturer: Hetero Healthcare Ltd

• Formulation: Fixed-dose combination of Protease Inhibitors

• Drug Class: Protease Inhibitors (PIs)

🧪 Composition (per tablet):

• Lopinavir – 200 mg

• Ritonavir – 50 mg

📌 Indications:

• Second-line antiretroviral therapy for HIV-1 infection

• Used in patients with resistance or failure of first-line ART regimens

• Acts as a "booster" (Ritonavir boosts Lopinavir levels)

⚙️ Mechanism of Action:

• Both drugs inhibit HIV protease enzyme, preventing viral maturation

• Ritonavir inhibits cytochrome P450 3A4 to increase Lopinavir plasma concentration

Additional Information:

• Delivery Time: 12-15 months

💊 Nevimune 200 mg Tablet

• Generic Name: Nevirapine

• Manufacturer: Cipla Ltd

• Drug Class: NNRTI (Non-Nucleoside Reverse Transcriptase Inhibitor)

🧪 Composition:

• Nevirapine – 200 mg

📌 Indications:

• Used in combination with other antiretroviral agents for the treatment of HIV-1 infection

• Also used to prevent mother-to-child transmission during childbirth in certain protocols

⚙️ Mechanism of Action:

Nevirapine binds directly to reverse transcriptase, blocking the RNA-to-DNA conversion process essential for HIV replication.

💡 Dosage & Administration:

• Standard initiation: 200 mg once daily for 14 days (to reduce rash risk), then 200 mg twice daily

• Must be used in combination therapy, not as monotherapy

🗓️ Shelf Life: 24–36 months 🧊 Storage: Store below 30°C, dry place 💊 Nevir 200 mg Tablet

• Generic Name: Nevirapine

• Manufacturer: Hetero Healthcare

• Drug Class: NNRTI

🧪 Composition:

• Nevirapine – 200 mg

📌 Indications:

Same as Nevimune — for use in combination ART in HIV-1 infections

⚙️ Mechanism of Action:

Inhibits reverse transcriptase by binding to an allosteric site and blocking viral DNA synthesis

💡 Dosage & Administration:

• Same as Nevimune — initiated at 200 mg once daily for 14 days, then increased to 200 mg twice daily

• Always used in combination with other ART drugs

🗓️ Shelf Life: 24–36 months 🧊 Storage: Below 30°C 💊 Nevir ER 400 mg Tablet

• Generic Name: Nevirapine Extended Release

• Manufacturer: Hetero Healthcare

• Drug Class: NNRTI

🧪 Composition:

• Nevirapine – 400 mg (Extended Release)

📌 Indications:

• For treatment of HIV-1 infection in patients who have tolerated 200 mg BID of immediate-release Nevirapine for at least 14 days

• Provides once-daily convenience

⚙️ Mechanism of Action:

Same as standard Nevirapine but formulated for extended release — maintains effective plasma levels for 24 hours

💡 Dosage & Administration:

• One tablet once daily after lead-in phase (initial 14 days on 200 mg IR Nevirapine BID)

• Must be used with at least two other antiretroviral agents

🗓️ Shelf Life: 24–36 months 🧊 Storage: Store at room temperature, below 30°C 💊 Nevivir 200 mg Tablet

• Generic Name: Nevirapine

• Manufacturer: Emcure Pharmaceuticals

• Drug Class: NNRTI

🧪 Composition:

• Nevirapine – 200 mg

📌 Indications:

• Part of combination therapy for HIV-1 infection

⚙️ Mechanism of Action:

Inhibits reverse transcriptase — same as others

💡 Dosage & Administration:

• Start with 200 mg once daily for 14 days, then switch to 200 mg twice daily

• Use as part of a combination antiretroviral regimen

🗓️ Shelf Life: Typically 24–36 months 🧊 Storage: Below 30°C, dry place

Additional Information:

• Delivery Time: 12-15 days

💊 1. Tenvir AF 25 mg Tablet

• Generic Name: Tenofovir Alafenamide (TAF)

• Manufacturer: Cipla Ltd

• Drug Class: NRTI (Nucleotide Reverse Transcriptase Inhibitor)

🧪 Composition:

• Tenofovir Alafenamide 25 mg

📌 Indications:

• Used in the treatment of HIV-1 infection (as part of combination ART)

• Treatment of chronic hepatitis B infection

⚙️ Mechanism of Action:

TAF is a prodrug of tenofovir, which inhibits HIV reverse transcriptase by incorporating into viral DNA and causing chain termination. Compared to TDF (Tenofovir DF), it delivers higher intracellular levels of active drug with lower systemic toxicity.

💡 Dosage & Administration:

• Typically 1 tablet once daily with or without food

• Must be part of a combination ART regimen

🗓️ Shelf Life: 24–36 months 🧊 Storage: Store below 30°C, dry place 💊 2. Tentide AF 25 mg Tablet

• Generic Name: Tenofovir Alafenamide (TAF)

• Manufacturer: Hetero Healthcare Ltd

• Drug Class: NRTI

🧪 Composition:

• Tenofovir Alafenamide 25 mg

📌 Indications:

• Treatment of HIV-1 and chronic HBV infections

⚙️ Mechanism of Action:

Same as Tenvir AF — provides targeted intracellular action with lower plasma exposure, hence improved renal and bone safety profile

💡 Dosage & Administration:

• Once daily with or without food

• Often used in combination packs or with Dolutegravir/Lamivudine

🗓️ Shelf Life: 24–36 months 🧊 Storage: Store in a cool, dry place 💊 3. Tenfoplus 25 mg Tablet

• Generic Name: Tenofovir Alafenamide (TAF)

• Manufacturer: Emcure Pharmaceuticals Ltd

• Drug Class: NRTI

🧪 Composition:

• Tenofovir Alafenamide 25 mg

📌 Indications:

• Used in HIV combination ART

• Approved for chronic hepatitis B

⚙️ Mechanism of Action:

Same as others — converts to active tenofovir diphosphate within cells, inhibiting reverse transcriptase.

💡 Dosage & Administration:

• 1 tablet daily (in combo therapy)

🗓️ Shelf Life: ~24–30 months 🧊 Storage: Room temperature, avoid humidity 💊 4. Tenohep AF 25 mg Tablet

• Generic Name: Tenofovir Alafenamide (TAF)

• Manufacturer: Zydus Lifesciences Ltd

• Drug Class: NRTI

🧪 Composition:

• Tenofovir Alafenamide 25 mg

📌 Indications:

• Primarily used in chronic Hepatitis B treatment

• Also applicable for HIV-1 in combination with other antiretrovirals

⚙️ Mechanism of Action:

Same as the others — inhibits reverse transcriptase; shows liver-focused delivery, making it more suitable for hepatitis B patients

💡 Dosage & Administration:

• Once daily orally, preferably as part of a structured regiment

🗓️ Shelf Life: ~36 months 🧊 Storage: Cool, dry place under 30°C

Additional Information:

• Delivery Time: 12-15 days

�� 1. Tenvir 300 mg Tablet

• Generic Name: Tenofovir Disoproxil Fumarate (TDF)

• Manufacturer: Cipla Ltd

• Drug Class: NRTI (Nucleotide Reverse Transcriptase Inhibitor)

�� Composition:

• Tenofovir Disoproxil Fumarate – 300 mg

�� Indications:

• Treatment of HIV-1 infection (in combination with other antiretrovirals)

• Treatment of chronic hepatitis B infection

⚙️ Mechanism of Action:

Converted into tenofovir diphosphate inside cells → inhibits reverse transcriptase enzyme → halts viral replication.

�� Dosage:

• 300 mg once daily, preferably with food

• Always used as part of combination antiretroviral therapy

��️ Shelf Life: 36 months �� Storage: Below 30°C, dry place �� 2. Hepdoze 300 mg Tablet

• Generic Name: Tenofovir Disoproxil Fumarate

• Manufacturer: Mylan/Viatris

• Drug Class: NRTI

�� Composition:

• Tenofovir Disoproxil Fumarate – 300 mg

�� Indications:

• Used in HIV (as part of ART)

• Also approved for chronic HBV

⚙️ Mechanism:

Same as above – inhibits reverse transcriptase by incorporating into viral DNA and causing chain termination

�� Dosage:

• 300 mg once daily

��️ Shelf Life: 24–36 months �� Storage: Room temperature, below 30°C �� 3. Tenfoclear 300 mg Tablet

• Generic Name: Tenofovir Disoproxil Fumarate

• Manufacturer: Hetero Healthcare

• Drug Class: NRTI

�� Composition:

• Tenofovir Disoproxil Fumarate – 300 mg

�� Indications:

• HIV-1 infection as part of triple drug therapy

• Chronic HBV infection

⚙️ Mechanism of Action:

Inhibits viral replication by interfering with reverse transcriptase, stopping DNA elongation

�� Dosage:

• 300 mg once daily

��️ Shelf Life: ~24–30 months �� Storage: Store in a cool, dry place �� 4. Tenohep 300 mg Tablet

• Generic Name: Tenofovir Disoproxil Fumarate

• Manufacturer: Zydus Lifesciences Ltd

• Drug Class: NRTI

�� Composition:

• Tenofovir Disoproxil Fumarate – 300 mg

�� Indications:

• Often prescribed for hepatitis B

• Also used in HIV regimens

⚙️ Mechanism:

Same as others – blocks viral reverse transcriptase enzyme by mimicking natural nucleotides

�� Dosage:

• 1 tablet daily (usually as part of a combination)

��️ Shelf Life: ~36 months �� Storage: Store below 30°C

Additional Information:

• Delivery Time: 12-15 days

💊 1. Valcip 450 mg Tablet

• Generic Name: Valganciclovir Hydrochloride

• Brand Name: Valcip

• Manufacturer: Cipla Ltd

• Strength: 450 mg

• Drug Class: Antiviral (Guanine nucleoside analog)

📌 Indications:

• Treatment of CMV retinitis in patients with AIDS

• Prevention of CMV infection in organ transplant recipients

⚙️ Mechanism of Action:

Valganciclovir is a prodrug of ganciclovir. Once converted, it:

• Inhibits viral DNA polymerase

• Gets incorporated into viral DNA → halts replication

💡 Dosage:

• CMV Retinitis (induction): 900 mg twice daily for 21 days

• Maintenance / Prevention: 900 mg once daily

• Renal dosing adjustments required

⚠️ Common Side Effects:

• Neutropenia, anemia, thrombocytopenia

• GI upset: nausea, vomiting, diarrhea

• Headache, fatigue

• Elevated liver enzymes (AST/ALT)

🗓️ Shelf Life: 24–36 months 🧊 Storage: Below 30°C, away from moisture ⭐ Notable:

• Most widely prescribed valganciclovir in India

• WHO & national ART programs often list it

💊 2. CMVee 450 mg Tablet

• Generic Name: Valganciclovir Hydrochloride

• Brand Name: CMVee

• Manufacturer: Emcure Pharmaceuticals

• Strength: 450 mg

• Drug Class: Antiviral

📌 Indications:

• CMV infections in immunocompromised adults

• Post-transplant CMV prevention

⚙️ Mechanism of Action:

Same as Valcip – converts to ganciclovir → stops viral DNA replication

💡 Dosage:

Follows same protocol: 900 mg/day or 900 mg twice daily during induction

⚠️ Side Effects:

• Hematologic suppression (monitor blood counts)

• GI disturbances

• Rare: neurotoxicity in high doses

🗓️ Shelf Life: Around 24 months 🧊 Storage: Store at controlled room temperature ⭐ Notable:

• Common in institutional and hospital tenders

• Cost-effective alternative

💊 3. Emval 450 mg Tablet

• Generic Name: Valganciclovir Hydrochloride

• Brand Name: Emval

• Manufacturer: Macleods Pharmaceuticals

• Strength: 450 mg

• Drug Class: Antiviral (CMV-specific)

📌 Indications:

• CMV retinitis in HIV patients

• CMV prophylaxis post kidney, liver, heart transplants

⚙️ Mechanism of Action:

Blocks CMV DNA polymerase by integrating false nucleotides → virus replication halts

💡 Dosage:

• 900 mg/day or bid based on stage

• Requires dose adjustment in kidney dysfunction

⚠️ Side Effects:

• Bone marrow suppression

• Headache, tremor

• Liver function disturbance

🗓️ Shelf Life: ~24 months 🧊 Storage: Cool, dry conditions ⭐ Notable:

• Less common but effective option for CMV therapy

• Sometimes preferred in non-branded tenders

Additional Information:

• Delivery Time: 12-15 days

💊 1. Valgacel 450 mg Tablet

• Generic Name: Valganciclovir Hydrochloride

• Brand Name: Valgacel

• Manufacturer: Glenmark Pharmaceuticals

• Strength: 450 mg

• Drug Class: Antiviral (Guanine nucleoside analog)

📌 Indications:

• Treatment of CMV retinitis in AIDS patients

• Prevention of CMV infection in organ transplant recipients

⚙️ Mechanism of Action:

• Prodrug converted to ganciclovir

• Inhibits viral DNA polymerase, stopping viral DNA synthesis and replication

💡 Dosage:

• Induction: 900 mg twice daily for 21 days

• Maintenance: 900 mg once daily

• Requires dose adjustment in renal impairment

⚠️ Side Effects:

• Bone marrow suppression (neutropenia, anemia)

• Nausea, diarrhea, headache

• Possible renal toxicity and liver enzyme elevation

🗓️ Shelf Life: 24–36 months 🧊 Storage: Store below 30°C in a dry place 💊 2. Cymgal 450 mg Tablet

• Generic Name: Valganciclovir Hydrochloride

• Brand Name: Cymgal

• Manufacturer: Cadila Pharmaceuticals

• Strength: 450 mg

• Drug Class: Antiviral

📌 Indications:

• CMV retinitis treatment in immunocompromised patients

• Prophylaxis against CMV post-transplantation

⚙️ Mechanism of Action:

• Converts to ganciclovir intracellularly

• Blocks viral DNA polymerase to inhibit CMV replication

💡 Dosage:

• Same as standard valganciclovir protocols

• Renal function monitoring recommended

⚠️ Side Effects:

• Hematologic effects like neutropenia

• GI upset (nausea, vomiting)

• Headache and fatigue

🗓️ Shelf Life: Approximately 24 months 🧊 Storage: Room temperature, away from moisture 💊 3. Virolfi 450 mg Tablet

• Generic Name: Valganciclovir Hydrochloride

• Brand Name: Virolfi

• Manufacturer: Lupin Pharmaceuticals

• Strength: 450 mg

• Drug Class: Antiviral

📌 Indications:

• CMV retinitis in AIDS

• CMV infection prophylaxis in transplant recipients

⚙️ Mechanism of Action:

• Prodrug of ganciclovir, inhibits viral DNA polymerase

• Stops CMV replication effectively

💡 Dosage:

• Induction and maintenance dosing as per guidelines

• Dose adjustment required for renal impairment

⚠️ Side Effects:

• Bone marrow suppression (monitor CBC)

• Gastrointestinal discomfort

• Rare neurologic symptoms

🗓️ Shelf Life: Around 24–30 months 🧊 Storage: Store in a cool, dry place

Additional Information:

• Delivery Time: 12-15 days

💊 Zidine 300 mg Tablet

• Generic Name: Zidovudine

• Brand Name: Zidine

• Strength: 300 mg

• Manufacturer: (Varies by region; commonly available from multiple manufacturers)

• Drug Class: Antiretroviral (Nucleoside Reverse Transcriptase Inhibitor - NRTI)

📌 Indications:

• Used in combination with other antiretroviral agents for the treatment of HIV-1 infection.

• Prevention of mother-to-child transmission of HIV during pregnancy, labor, and delivery.

• Post-exposure prophylaxis following potential HIV exposure.

⚙️ Mechanism of Action:

• Zidovudine is a nucleoside analogue that inhibits the activity of HIV reverse transcriptase.

• It gets incorporated into viral DNA, causing premature termination of DNA chain elongation, thus preventing viral replication.

💡 Dosage & Administration:

• Typical adult dose: 300 mg orally twice daily.

• Dosage adjustments may be necessary in patients with renal impairment.

• Should always be used as part of a combination antiretroviral therapy (ART) regimen.

🗓️ Shelf Life: Typically 24 to 36 months 🧊 Storage: Store below 30°C, protect from moisture and light 🔑 Key Points:

• Zidovudine (Zidine) was the first approved antiretroviral drug and remains important in HIV treatment.

• Monitoring blood counts regularly is essential due to risk of bone marrow suppression.

• Usually combined with other antiretrovirals for optimal viral suppression.

Additional Information:

• Delivery Time: 12-15 days

💊 Abec-L Tablet

• Composition:

  • Abacavir (ABC) – 600 mg

  • Lamivudine (3TC) – 300 mg

• Drug Class: Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

🧬 Mechanism of Action:

Both Abacavir and Lamivudine inhibit the reverse transcriptase enzyme of HIV, preventing viral replication by blocking the conversion of viral RNA into DNA.

✅ Indications:

• Used in combination with other antiretroviral agents for the treatment of HIV-1 infection.

• Commonly included in first-line ART regimens, especially where Dolutegravir is added separately.

🕒 Dosage:

• One tablet once daily, with or without food.

• Often taken alongside a third drug like Dolutegravir or Efavirenz for complete therapy.

📦 Shelf Life:

• 24–36 months from the date of manufacture.

• Store below 30°C, away from moisture and heat.

🏷️ Manufacturer:

• Commonly manufactured by Emcure Pharmaceuticals and Hetero Healthcare in India.

🔍 Key Advantages:

• Two essential NRTIs in a single pill, reducing pill burden.

• Often used in resource-limited settings due to its cost-effectiveness.

• Used when Inbec or Triumeq are not available or not suitable.

Additional Information:

• Delivery Time: 12-15 days

💊 Twinaqt Tablet

Generic Name: Dolutegravir 50 mg + Lamivudine 300 mg
Manufacturer: Emcure Pharmaceuticals Ltd

📌 Description:

Twinaqt is a fixed-dose combination antiretroviral used in the treatment of HIV-1 infection. It contains:

• Dolutegravir (50 mg) – an integrase strand transfer inhibitor (INSTI)

• Lamivudine (300 mg) – a nucleoside reverse transcriptase inhibitor (NRTI)

This combination offers a 2-drug regimen option for HIV-1 treatment, ideal for certain stable patients, particularly those who are already virally suppressed.

🧪 Composition (per tablet):

• Dolutegravir 50 mg

• Lamivudine 300 mg

💡 Indication / Uses:

• Treatment of HIV-1 infection in adults and adolescents weighing ≥35 kg

• Usually prescribed as a maintenance regimen for patients who are already virologically suppressed and without history of resistance

📆 Dosage:

• One tablet once daily, with or without food

• Should be taken regularly at the same time each day

✅ Advantages:

• Simplified 2-drug regimen for eligible patients

• Less pill burden, improving patient adherence

• Lower long-term toxicity (compared to 3-drug regimens in stable patients)

• High resistance barrier due to Dolutegravir

🗓️ Shelf Life:

• 24 months (2 years) from the date of manufacture

• Store below 30°C, in a dry place away from sunlight and moisture

Additional Information:

• Delivery Time: 12-15 days

💊 1. Viraday Tablet

Manufacturer: Cipla Ltd
Generic Composition:

• Tenofovir Disoproxil Fumarate (TDF) 300 mg

• Lamivudine 300 mg

• Efavirenz 600 mg

📌 Description:
Viraday is one of the most trusted and oldest brands of TLE (Tenofovir + Lamivudine + Efavirenz) used in the treatment of HIV-1 infection.
It is often used as a once-daily, single-pill regimen for adults and adolescents.
Viraday has strong international recognition and is widely prescribed for export as well as private-sector HIV therapy.

💡 Uses:

• First-line antiretroviral therapy for HIV

• Post-exposure prophylaxis (off-label)

📆 Dosage:

• 1 tablet once daily, preferably at bedtime (to reduce dizziness, vivid dreams)

 

💊 2. Vonavir Tablet

Manufacturer: Emcure Pharmaceuticals
Generic Composition:

• Tenofovir Disoproxil Fumarate (TDF) 300 mg

• Lamivudine 300 mg

• Efavirenz 600 mg

📌 Description:
Vonavir is a cost-effective Indian generic for the TLE regimen, used widely in government ART programs, low-cost hospitals, and by NGOs.
It offers equivalent efficacy to Viraday but at a more economical price point.

💡 Uses:

• First-line HIV treatment

• Substitution in patients already on TLE

📆 Dosage:

• One tablet daily, ideally at night

💊 3. Teevir Tablet

Manufacturer: Hetero Healthcare
Generic Composition:

• Tenofovir Disoproxil Fumarate (TDF) 300 mg

• Lamivudine 300 mg

• Efavirenz 600 mg

📌 Description:
Teevir is a popular generic TLE formulation widely distributed through public-private partnerships, HIV screening camps, and district-level ART centers.
It balances cost with availability, making it a go-to in rural and semi-urban areas.

💡 Uses:

• Management of HIV-1 infection

• Works well as initial or continued ART

📆 Dosage:

• 1 tablet daily, bedtime preferred

 

💊 4. Trustiva Tablet

Manufacturer: Laurus Labs
Generic Composition:

• Tenofovir Disoproxil Fumarate (TDF) 300 mg

• Lamivudine 300 mg

• Efavirenz 600 mg

📌 Description:
Trustiva is a newer yet high-quality TLE product from Laurus Labs, a globally reputed API and formulation manufacturer.
It is WHO-GMP compliant and often used in international tenders and export markets.
It is gaining popularity due to its balance of price, quality, and availability.

💡 Uses:

• Antiretroviral therapy for adults

• Used in both national and international HIV programs

📆 Dosage:

• One tablet daily, preferably at night

Additional Information:

• Delivery Time: 12-15 days

💊 1. Vonaday Tablet

Manufacturer: Hetero Healthcare
Drug Class: Fixed-dose combination antiretroviral therapy
Composition:

• Tenofovir Disoproxil Fumarate (TDF) – 300 mg

• Lamivudine – 300 mg

• Efavirenz – 600 mg

📌 Description:
Vonaday is a once-daily antiretroviral used in the treatment of HIV-1 infection in adults. It is part of India's national ART program and is also prescribed in the private sector due to its balance of cost and quality. Produced by Hetero, one of India's largest ARV suppliers, it is considered a standard TLE brand.

📆 Dosage:

• 1 tablet at bedtime daily, ideally on an empty stomach to reduce CNS side effects from Efavirenz.

💡 Uses:

• First-line HIV therapy

• Effective in viral suppression

• Also used in post-exposure prophylaxis (PEP) (off-label)

💊 2. Telura Tablet

Manufacturer: Mylan (Viatris)
Drug Class: Antiretroviral (TLE) combination
Composition:

• Tenofovir Disoproxil Fumarate (TDF) – 300 mg

• Lamivudine – 300 mg

• Efavirenz – 600 mg

📌 Description:
Telura is one of the most internationally trusted TLE tablets. Manufactured by Mylan, now part of Viatris, it's used extensively in PEPFAR, UN programs, and international HIV treatment programs. Known for stringent quality standards, Telura is WHO-prequalified and widely exported.

📆 Dosage:

• Take 1 tablet once daily, preferably at bedtime.

💡 Uses:

• Long-term HIV treatment

• Used in both public health and private clinics globally

 

💊 3. Vianca Tablet

Manufacturer: Strides Pharma
Drug Class: Antiretroviral therapy
Composition:

• Tenofovir Disoproxil Fumarate (TDF) – 300 mg

• Lamivudine – 300 mg

• Efavirenz – 600 mg

📌 Description:
Vianca is a generic fixed-dose TLE tablet formulated by Strides, known for supplying generic ARVs to many parts of Africa and Asia. It is cost-effective, with moderate use in India and growing presence in export markets.

📆 Dosage:

• 1 tablet daily, preferably at bedtime.

💡 Uses:

• HIV-1 treatment

• Can be considered in resource-limited settings

 

💊 4. Tenolam E Tablet

Manufacturer: Hetero Healthcare
Drug Class: TLE (Triple drug combination)
Composition:

• Tenofovir Disoproxil Fumarate (TDF) – 300 mg

• Lamivudine – 300 mg

• Efavirenz – 600 mg

📌 Description:
Tenolam E is another TLE combination from Hetero, mainly intended for hospital and pharmacy supply at a budget-friendly rate. It is essentially an alternate branding of Vonaday with similar content but used in bulk procurement and stock substitution.

📆 Dosage:

• 1 tablet once a day at night

💡 Uses:

• Effective for HIV-1 suppression

• Works identically to other TLE options

Additional Information:

• Delivery Time: 12-15 days

💊 1. Duovir-E Kit

Manufacturer: Cipla Ltd
Drug Class: Antiretroviral Combination Therapy (Kit)
Indication: Treatment of HIV-1 infection

📦 Kit Composition:

Each Duovir-E Kit contains:

• 1 tablet of Efavirenz 600 mg

• 1 tablet of Lamivudine 150 mg + Zidovudine 300 mg

These are taken together once daily — typically at bedtime.

📌 Description:

Duovir-E Kit is a widely trusted first-line antiretroviral therapy by Cipla, combining three potent HIV medications into a two-pill kit. It is especially useful where fixed-dose triple combinations are not feasible or in resource-limited settings.

Cipla’s brand is widely used in India, Africa, and parts of Southeast Asia due to strong distribution and inclusion in national ART programs.

💡 Mechanism of Action:

• Efavirenz – NNRTI: blocks reverse transcriptase

• Lamivudine + Zidovudine – NRTIs: inhibit viral DNA synthesis

Together, they suppress HIV replication and reduce viral load.

📆 Dosage:

• Take both tablets once daily, preferably at bedtime on an empty stomach (to minimize Efavirenz-related CNS effects)

🗓️ Shelf Life:

• 24 months from manufacturing

• Store in a cool, dry place below 30°C

✅ Key Advantages:

• Cipla’s quality & trust

• WHO-GMP compliant

• Often supplied via NGOs & public tenders

• Strong track record in viral suppression

💊 2. Lazid-E Kit

Manufacturer: Hetero Healthcare
Drug Class: Antiretroviral Combination Therapy (Kit)
Indication: HIV-1 infection management

📦 Kit Composition:

Each Lazid-E Kit includes:

• 1 tablet of Efavirenz 600 mg

• 1 tablet of Lamivudine 150 mg + Zidovudine 300 mg

Same regimen as Duovir-E, taken together once daily.

📌 Description:

Lazid-E Kit by Hetero is a cost-effective ARV kit, used in first-line HIV treatment regimens. It contains the same WHO-recommended drugs as Duovir-E and is manufactured under stringent GMP conditions.

While not as widely used as Cipla's kit, it is still trusted in many private setups and tenders, especially where affordability is key.

💡 Mechanism of Action:

Same as Duovir-E — triple ARV combination working synergistically to inhibit HIV replication.

📆 Dosage:

• Take both tablets once daily, ideally at night

• Can be taken with water, on an empty stomach

🗓️ Shelf Life:

• 24 months

• Store below 30°C

✅ Key Advantages:

• Budget-friendly option

• WHO-GMP certified by Hetero

• Reliable alternate to Duovir-E

• Flexible use in institutions and low-cost programs

Additional Information:

• Delivery Time: 12-15 days

💊 1. Tenof-EM Tablet

Manufacturer: Hetero Healthcare
Drug Type: TDF-based ART / PrEP
Composition:

• Tenofovir Disoproxil Fumarate (TDF) – 300 mg

• Emtricitabine – 200 mg

📌 Description:

Tenof-EM is one of the most widely used Tenofovir + Emtricitabine combinations in HIV treatment and prevention (PrEP). Manufactured by Hetero, it’s part of national and global HIV programs, including PEPFAR and NACO India.

💡 Uses:

• HIV-1 treatment (part of triple therapy)

• PrEP (Pre-Exposure Prophylaxis)

• PEP (Post-Exposure Prophylaxis) (with other drugs)

🗓️ Shelf Life:

• 24 to 36 months

💊 2. Tafero-EM Tablet

Manufacturer: Hetero Healthcare
Drug Type: TAF-based ART / PrEP
Composition:

• Tenofovir Alafenamide (TAF) – 25 mg

• Emtricitabine – 200 mg

📌 Description:

Tafero-EM is a new-generation HIV medication that uses TAF, a safer prodrug of Tenofovir. It achieves high antiviral activity at a lower dose, reducing risk to kidneys and bones.

It is increasingly used for long-term treatment and is part of modern PrEP protocols in some countries.

💡 Uses:

• Long-term HIV-1 treatment

• PrEP (preferred for patients with renal risk)

🗓️ Shelf Life:

• 24 months

💊 3. Tavin-EM Tablet

Manufacturer: Emcure Pharmaceuticals
Drug Type: TDF-based ART / PrEP
Composition:

• Tenofovir Disoproxil Fumarate (TDF) – 300 mg

• Emtricitabine – 200 mg

📌 Description:

Tavin-EM is a generic Tenofovir-Emtricitabine tablet produced by Emcure. It is used in both treatment regimens and prevention protocols like PrEP or PEP, mostly in India and a few export markets.

Not as widely used as Tenof-EM but still recognized for quality.

💡 Uses:

• HIV treatment (triple therapy)

• PrEP and PEP regiment

💊 4. Taficita Tablet

Manufacturer: Mylan (now part of Viatris)
Drug Type: TAF-based ART / PrEP
Composition:

• Tenofovir Alafenamide (TAF) – 25 mg

• Emtricitabine – 200 mg

📌 Description:

Taficita is a premium quality TAF-based tablet, WHO-prequalified and exported globally. Often used in combination with Dolutegravir (as part of TLD or TAF-based ART regimens).

Preferred where quality assurance and international compliance are required.

💡 Uses:

• HIV treatment

• PrEP (especially for at-risk individuals with renal issues)

💊 5. Emtaf Tablet

Manufacturer: Cipla
Drug Type: TDF-based ART
Composition:

• Tenofovir Disoproxil Fumarate (TDF) – 300 mg

• Emtricitabine – 200 mg

📌 Description:

Emtaf by Cipla is a reliable TDF-based combination, part of the company’s long-standing HIV portfolio. It is used in combination therapies and for PrEP in select protocols. Its usage is moderate, less than Tenof-EM.

💡 Uses:

• First-line HIV therapy

• PrEP/PEP in selected contexts

Additional Information:

• Delivery Time: 12-15 days

💊 Tavin LN Kit

• Brand: Tavin LN Kit

• Manufacturer: Emcure Pharmaceuticals Ltd

• Formulation: Oral Fixed-Dose Combination Therapy

• Therapeutic Class: Antiretroviral (ARV) – NRTIs + NNRTI

• Use: HIV-1 infection treatment

🧪 Composition (Per Kit Contains 3 Tablets):

Each daily kit typically includes:

• Tenofovir Disoproxil Fumarate – 300 mg

• Lamivudine – 300 mg

• Nevirapine – 200 mg

These three drugs act synergistically to suppress HIV replication and reduce viral load in patients.

📌 Indications / Uses:

• First-line treatment of HIV-1 infection in adults and adolescents

• Especially common in resource-limited settings

• Part of Highly Active Antiretroviral Therapy (HAART)

⚙️ Mechanism of Action:

• Tenofovir and Lamivudine: Nucleoside Reverse Transcriptase Inhibitors (NRTIs) – block reverse transcriptase, halting virus replication

• Nevirapine: Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) – binds directly to reverse transcriptase and inhibits enzyme activity

Together, the combination helps:

• Lower viral load

• Increase CD4+ T-cell counts

• Delay HIV progression

💡 Dosage & Administration:

• One full kit (3 tablets) once daily, or as advised by the doctor

• Nevirapine lead-in phase: often started with a lower dose of Nevirapine (e.g., 200 mg once daily for 14 days) to reduce risk of rash or liver toxicity

• Tablets can be taken with or without food, preferably at the same time each day

🗓️ Storage and Shelf Life:

• Store below 30°C, in a cool and dry place

• Protect from moisture and direct sunlight

• Shelf life: Around 24 to 36 months from manufacturing date

Additional Information:

• Delivery Time: 12-15 days

💊 Duovir N Tablet

• Manufacturer: Cipla Ltd

• Formulation: Fixed-dose combination (Triple drug)

• Drug Class: NRTIs + NNRTI

🧪 Composition (per tablet):

• Lamivudine – 150 mg

• Zidovudine – 300 mg

• Nevirapine – 200 mg

📌 Indications:

• Treatment of HIV-1 infection in adults and adolescents

• Used as part of first-line antiretroviral therapy (ART)

⚙️ Mechanism of Action:

• Lamivudine & Zidovudine: Nucleoside Reverse Transcriptase Inhibitors (NRTIs) – inhibit viral DNA synthesis

• Nevirapine: Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) – binds reverse transcriptase directly

💡 Dosage:

• Typically one tablet twice daily, or as prescribed

• Nevirapine requires a lead-in period (usually 14 days at a lower dose)

🗓️ Shelf Life: 24–36 months 🧊 Storage: Below 30°C in a cool, dry place 💊 Lazid N Tablet

• Manufacturer: Hetero Healthcare Ltd

• Formulation: Triple drug fixed-dose combination

• Drug Class: NRTIs + NNRTI

🧪 Composition (per tablet):

• Lamivudine – 150 mg

• Zidovudine – 300 mg

• Nevirapine – 200 mg

📌 Indications:

• HIV-1 infection in treatment-naive patients or as part of combination ART

💡 Dosage & Administration:

• One tablet twice daily, post Nevirapine initiation with a lead-in period

• Should be taken consistently at the same time each day

🗓️ shelf Life: 2–3 years 🧊 Storage: Room temperature, dry area 💊 Zidolam N Tablet

• Manufacturer: Emcure Pharmaceuticals Ltd

• Formulation: Fixed-dose triple combination

• Drug Class: NRTIs + NNRTI

🧪 Composition (per tablet):

• Lamivudine – 150 mg

• Zidovudine – 300 mg

• Nevirapine – 200 mg

📌 Uses:

• Treatment of HIV-1 as part of combination ART

• Suitable for adult patients

💡 Administration:

• Twice daily dosing, with appropriate lead-in for Nevirapine

• Usually taken regardless of meals, with water

🗓️ Shelf Life: Approx. 36 months 🧊 Storage: Cool, dry place below 30°C

Additional Information:

• Delivery Time: 12-15 days

💊 Tavin L Tablet

• Manufacturer: Emcure Pharmaceuticals Ltd

• Formulation: Fixed-dose combination oral tablet

• Drug Class: Antiretroviral Therapy (ART) – Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

🧪 Composition (per tablet):

• Tenofovir Disoproxil Fumarate (TDF): 300 mg

• Lamivudine (3TC): 300 mg

📌 Indications:

• Treatment of HIV-1 infection in adults and adolescents

• Used as part of first-line combination antiretroviral therapy (ART)

• Suitable for patients requiring dual NRTI backbone therapy

⚙️ Mechanism of Action:

• Tenofovir and Lamivudine are nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs).

• They inhibit the HIV reverse transcriptase enzyme, preventing the conversion of viral RNA into DNA, which blocks viral replication.

💡 Dosage & Administration:

• Typically, one tablet taken once daily, or as prescribed by a healthcare professional.

• Can be taken with or without food.

• Adherence to dosing schedule is critical for efficacy and to prevent resistance.

🗓️ Storage:

• Store in a cool, dry place below 30°C.

• Keep away from direct sunlight and moisture.

• Keep out of reach of children.

Additional Information:

• Delivery Time: 12-15 days

💊 Duovir Tablet

• Manufacturer: Cipla Ltd

• Formulation: Fixed-dose combination tablet

• Drug Class: Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

🧪 Composition (per tablet):

• Lamivudine (3TC): 150 mg

• Zidovudine (AZT): 300 mg

📌 Indications:

• Treatment of HIV-1 infection in adults and adolescents

• Used as part of combination antiretroviral therapy (ART)

• Effective in reducing viral load and improving immune function

⚙️ Mechanism of Action:

• Both drugs inhibit reverse transcriptase, an enzyme essential for HIV replication.

• Lamivudine and Zidovudine act as nucleoside analogues that get incorporated into viral DNA and cause chain termination.

💡 Dosage & Administration:

• Typically, one tablet twice daily or as directed by a physician.

• Can be taken with or without food.

• Adherence to prescribed regimen is critical.

⚠️ Side Effects:

• Common: headache, nausea, fatigue, anemia (due to zidovudine), gastrointestinal discomfort

• Rare: neutropenia, liver enzyme elevation, hypersensitivity reactions

🗓️ Shelf Life: 24 to 36 months 🧊 Storage: Store below 30°C, keep in a dry place away from sunlight. 💊 Lazid Tablet

• Manufacturer: Hetero Healthcare Ltd

• Formulation: Fixed-dose combination tablet

• Drug Class: Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

🧪 Composition (per tablet):

• Lamivudine (3TC): 150 mg

• Zidovudine (AZT): 300 mg

📌 Indications:

• HIV-1 infection treatment in adults and adolescents

• Part of antiretroviral therapy (ART) regimens

• Helps decrease viral load and increase CD4+ cell count

⚙️ Mechanism of Action:

• Lamivudine and Zidovudine block reverse transcriptase activity, preventing HIV replication and infection spread.

💡 Dosage & Administration:

• Generally one tablet twice daily, or as prescribed.

• May be taken with or without meals.

• Consistency in timing enhances effectiveness.

🗓️ Shelf Life: Approximately 2 to 3 years 🧊 Storage: Store in a cool, dry place below 30°C away from direct light.

Additional Information:

• Delivery Time: 12-15 days

💊 1. Reatix Kit

Contents (Fixed-Dose Combination):

• Tenofovir Disoproxil Fumarate 300 mg

• Lamivudine 300 mg

• Efavirenz 600 mg

Description:
Reatix Kit is an antiretroviral medication used for the treatment of HIV-1 infection in adults and adolescents. It contains a triple combination of drugs in a single dose, simplifying therapy. The combination inhibits the reverse transcriptase enzyme, preventing the replication of HIV.

• Tenofovir: A nucleotide reverse transcriptase inhibitor (NRTI)

• Lamivudine: A nucleoside reverse transcriptase inhibitor (NRTI)

• Efavirenz: A non-nucleoside reverse transcriptase inhibitor (NNRTI)

Administration:

• One tablet daily, preferably at bedtime to reduce side effects.

Common Side Effects:

• Dizziness, insomnia, vivid dreams, fatigue, rash.

Shelf Life:

• 24 to 36 months, depending on the batch and manufacturer.

💊 2. Viro 4 Kit

Contents:

• Tenofovir Disoproxil Fumarate 300 mg

• Lamivudine 300 mg

• Efavirenz 600 mg

Description:
Viro 4 Kit contains the same combination as Reatix and is also used as first-line therapy in HIV treatment. It is typically manufactured by different pharmaceutical companies and may be preferred where price or brand availability is a factor.

Mechanism:

• Inhibits HIV replication by targeting different stages of reverse transcription.

Administration:

• Once daily, preferably at night.

Side Effects:

• Similar to Reatix: CNS effects (like sleep disturbances), rash, fatigue.

Shelf Life:

• 24 to 36 months

💊 3. Tenolam AR Kit

Contents:

• Tenofovir Disoproxil Fumarate 300 mg

• Lamivudine 300 mg

• Atazanavir 300 mg

• Ritonavir 100 mg

Description:
Tenolam AR Kit is used for second-line HIV treatment, typically when patients show resistance to first-line drugs like Efavirenz. The addition of Atazanavir (a protease inhibitor) and Ritonavir (a booster) enhances the antiretroviral activity by targeting a different step in the HIV life cycle.

• Ritonavir boosts Atazanavir levels by inhibiting its metabolism.

• Suitable for patients who have experienced Efavirenz toxicity or resistance.

Administration:

• Usually once daily with food to improve absorption.

Common Side Effects:

• Jaundice (bilirubin increase), GI upset, lipid changes, nausea.

Shelf Life:

• 24 months typically

Additional Information:

• Delivery Time: 12-15 days

💊 Taffic Tablet

Manufacturer: Hetero Healthcare
Composition: Fixed-dose combination of three antiretroviral agents:

• Tenofovir Alafenamide (TAF) 25 mg

• Emtricitabine (FTC) 200 mg

• Dolutegravir (DTG) 50 mg

📄 Description:

Taffic is a once-daily, single-tablet regimen for the treatment of HIV-1 infection. It combines:

• Tenofovir Alafenamide (TAF) – a nucleotide reverse transcriptase inhibitor (NRTI), with improved renal and bone safety compared to TDF.

• Emtricitabine (FTC) – a potent NRTI that blocks HIV replication.

• Dolutegravir (DTG) – an integrase strand transfer inhibitor (INSTI) that prevents HIV from integrating into the host DNA.

✅ Indications:

• First-line treatment for HIV-1 in adults and adolescents weighing ≥35 kg.

• Used either in ART-naïve patients or as a switch therapy for those virologically suppressed.

💊 Dosage:

• One tablet daily, with or without food.

• Should be taken at the same time every day.

⚠️ Warnings & Precautions:

• Monitor liver function in patients with hepatitis co-infection.

• Not recommended for patients with known resistance to integrase inhibitors.

• Assess renal function before and during treatment.

📦 Shelf Life:

• 24 months from date of manufacture if stored properly below 30°C.

Additional Information:

• Delivery Time: 12-15 days

💊 Spegra Tablet

Generic Name: Dolutegravir 50 mg + Emtricitabine 200 mg + Tenofovir Alafenamide (TAF) 25 mg
Manufacturer: Emcure Pharmaceuticals Ltd

📌 Description:
Spegra is a fixed-dose combination antiretroviral therapy (ART) tablet used for the treatment of HIV-1 infection. It combines three potent agents from two classes:

• Dolutegravir (INSTI) – blocks HIV integrase enzyme to prevent viral replication

• Emtricitabine (NRTI) – inhibits reverse transcriptase enzyme

• Tenofovir Alafenamide (NRTI) – newer, safer prodrug form of tenofovir, with better kidney and bone safety than TDF

It is designed as a once-daily single-pill regimen to simplify HIV treatment and improve adherence.

🧪 Composition (per tablet):

• Dolutegravir: 50 mg

• Emtricitabine: 200 mg

• Tenofovir Alafenamide (TAF): 25 mg

💡 Indication / Uses:

• First-line therapy for treatment-naive adults and adolescents with HIV-1 infection

• Can be used as maintenance therapy in virologically suppressed patients when switching from another ART regimen

📆 Dosage:

• One tablet once daily, with or without food

• Must be taken exactly as prescribed to prevent resistance

Additional Information:

• Delivery Time: 12-15 days

💊 1. Xapavir LT

Generic Name: Lamivudine 300 mg + Tenofovir Disoproxil Fumarate (TDF) 300 mg + Dolutegravir 50 mg
Manufacturer: Emcure Pharmaceuticals

📌 Description:
Xapavir LT is a fixed-dose combination antiretroviral tablet, representing a TLD regimen, recommended as first-line therapy for HIV-1 infection.

• Lamivudine: A nucleoside reverse transcriptase inhibitor (NRTI)

• Tenofovir Disoproxil Fumarate (TDF): Another NRTI

• Dolutegravir: An integrase strand transfer inhibitor (INSTI)

This triple combination blocks viral replication and strengthens the immune system.

🧪 Composition:

• Lamivudine 300 mg

• Tenofovir Disoproxil Fumarate 300 mg

• Dolutegravir 50 mg

💡 Uses:

• First-line treatment of HIV-1 infection

• Suitable for adults and adolescents weighing ≥35 kg

📆 Dosage:

• 1 tablet once daily, with or without food

🗓️ Shelf Life:

• 24 months from manufacture

💊 2. Acriptega

Generic Name: Tenofovir Disoproxil Fumarate (TDF) 300 mg + Lamivudine 300 mg + Dolutegravir 50 mg
Manufacturer: Mylan (Viatris)

📌 Description:
Acriptega is a globally trusted single-tablet regimen (STR) for HIV-1 treatment, containing the WHO-recommended TLD components.
It is widely used in international HIV programs for its high quality and consistent availability.

🧪 Composition:

• Tenofovir Disoproxil Fumarate 300 mg

• Lamivudine 300 mg

• Dolutegravir 50 mg

💡 Uses:

• First-line and maintenance therapy for HIV-1 infection

• Used across global programs like PEPFAR, Global Fund

📆 Dosage:

• 1 tablet once daily

 

🗓️ Shelf Life:

• 24 months to 36 months (check pack)

🌍 Trusted Worldwide:

• WHO prequalified

• Used in over 100 countries

• High production standards

💊 3. Viropil

Generic Name: Tenofovir Disoproxil Fumarate (TDF) 300 mg + Lamivudine 300 mg + Dolutegravir 50 mg
Manufacturer: Hetero Healthcare

📌 Description:
Viropil is another widely used TLD-based triple drug combination, known for its cost-effectiveness and availability in Indian and regional markets.
It is a go-to ART for many doctors in India due to its proven efficacy and affordability.

🧪 Composition:

• Tenofovir Disoproxil Fumarate 300 mg

• Lamivudine 300 mg

• Dolutegravir 50 mg

💡 Uses:

• First-line treatment for HIV-1 infection

• Can be continued long-term if well tolerated

📆 Dosage:

• One tablet daily, with or without food

🗓️ Shelf Life:

• 24 months from manufacture

Additional Information:

• Delivery Time: 12-15 days

Item Code: CLT-61006

Lamivudine (2',3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.

IRESSA (gefitinib), indicated in Europe for the treatment of adults with locally advanced or metastatic NSCLC with activating mutations of EGFR-TK.

Iressa-Gefitinib Tablets (Astra Zeneca) 250mg

Item Code: CA-61100614456


Abamune (Abacavir) is used for reating HIV infection with other medications. Abacavir is a nucleoside analog reverse transcriptase inhibitor (NRTI). It works by slowing down the growth of HIV, the virus that causes AIDS.

Before using Abamune (Abacavir)

Some medical conditions may interact with Abamune (Abacavir). Tell your physician or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• If you are pregnant, planning to become pregnant, or are breast-feeding or thinking about breast-feeding
• If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• If you have allergies to medicines, foods, or other substances
• If you are unusually tired or have a fever, nausea, vomiting, diarrhea, stomach pain, a cough, or a skin rash
• If you have shortness of breath, an allergic reaction, or a sore throat

Some medicines may interact with Abamune (Abacavir) . Tell your physician if you are taking any other medicines, especially any of the following:

• because the effectiveness may be decreased by Abamune (Abacavir)
• Alcohol because the side effects and toxic effects of Abamune (Abacavir) may be increased

This may not be a complete list of all interactions that may occur. Ask your physician if Abamune (Abacavir) may interact with other medicines that you take. Check with your physician before you start, stop, or change the dose of any medicine.

Please contact us via email at for the detailed product and price list.We assure you for the quality supply and error free services from our side..you can get in touch email

Item Code: CNT-62806

Nelfinavir (Viracept) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV). Nelfinavir belongs to the class of drugs known as protease inhibitors (PIs) and like other PIs is generally used in combination with other antiretroviral drugs.

Nelfinavir mesylate (Viracept, formally AG1343) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2nM) and is being widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection.