Anti Hiv Medicine

💊 Vilitra 10 mg

Composition:

• Contains 10 mg of Vardenafil, a PDE5 inhibitor.

Uses:

• Primarily prescribed for men experiencing mild erectile dysfunction (ED).

• Often recommended for first-time users or those sensitive to medication.

Mechanism of Action:

• Works by relaxing blood vessels in the penis, allowing increased blood flow during sexual stimulation, which helps achieve and maintain an erection.

Onset & Duration:

• Starts working within 30 to 45 minutes after oral intake.

• Effects last approximately 4 to 5 hours.

Dosage:

• Usually taken 1 hour before sexual activity.

• Maximum frequency: once per day.

Side Effects:

• Mild and may include headache, flushing, nasal congestion, and dizziness.

• Lower dose reduces risk of side effects.

Precautions:

• Not to be combined with nitrates or certain heart medications.

• Use cautiously if you have cardiovascular problems.

💊 Vilitra 20 mg (Most Widely Used Dose)

Composition:

• Contains 20 mg of Vardenafil.

Uses:

• Standard dose for mild to moderate ED.

• Most commonly prescribed due to balance of effectiveness and tolerability.

Mechanism of Action:

• Same as 10 mg but stronger effect for better erectile response.

Onset & Duration:

• Effects begin in 30 to 45 minutes.

• Lasts approximately 5 to 6 hours, allowing flexibility.

Dosage:

• Taken about 1 hour before sexual activity.

• Maximum once daily use recommended.

Precautions:

• Same as 10 mg; avoid nitrates and consult doctor if heart disease is present.

💊 Vilitra 40 mg

Composition:

• Contains 40 mg of Vardenafil.

Uses:

• Prescribed for moderate to severe ED when lower doses are insufficient.

Mechanism of Action:

• Potent PDE5 inhibition for enhanced blood flow and erection strength.

Onset & Duration:

• Onset still 30-45 minutes.

• Effects can last up to 6 to 8 hours, providing longer window for sexual activity.

Dosage:

• Taken 1 hour before intercourse; max once daily.

Precautions:

• Greater caution with cardiovascular diseases or concurrent medications.

• Avoid use with nitrates completely.

💊 Vilitra 60 mg

Composition:

• Contains 60 mg of Vardenafil.

Uses:

• Reserved for severe or treatment-resistant ED cases where lower doses have failed.

Mechanism of Action:

• Strongest PDE5 inhibition among Vilitra doses; maximizes penile blood flow.

Onset & Duration:

• Effects start within 30-45 minutes.

• Duration may extend beyond 8 hours in some cases.

Dosage:

• Strictly under medical supervision; taken 1 hour prior to sexual activity.

�� Inbec Capsule

• Composition (Fixed-Dose Combination):

  • Abacavir (ABC) – 600 mg

  • Dolutegravir (DTG) – 50 mg

  • Lamivudine (3TC) – 300 mg

• Drug Class:

  • Abacavir & Lamivudine – Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

  • Dolutegravir – Integrase Strand Transfer Inhibitor (INSTI)

• Manufacturer: Emcure Pharmaceuticals

�� Mechanism of Action:

• Abacavir & Lamivudine inhibit the reverse transcriptase enzyme, blocking the conversion of viral RNA into DNA.

• Dolutegravir blocks the integrase enzyme, preventing integration of HIV DNA into the host genome — a crucial step in HIV replication.

✅ Indications:

• First-line treatment of HIV-1 infection in adults and adolescents over 12 years old and weighing at least 40 kg.

• Used as part of Antiretroviral Therapy (ART).

�� Dosage:

• One capsule once daily, preferably at the same time every day.

• Take with or without food.

�� Shelf Life:

• Generally 24–36 months from the date of manufacture.

• Store below 30°C in a dry place.

�� Key Advantages:

• Single daily pill simplifies HIV therapy.

• Contains Dolutegravir, a potent drug with high barrier to resistance.

• Suitable for initial ART regimens and recommended by WHO and national guidelines.