Erectile Dysfuntion Medicines

💊 Vidalista 2.5 mg

• Purpose: Low-dose tadalafil, often used as daily therapy to improve erectile function consistently over time.

• Usage: Suitable for men who want spontaneous sexual activity without planning the timing of the dose.

• Benefits: Helps maintain erectile function, fewer side effects due to low dose.

💊 Vidalista 5 mg

• Purpose: Also commonly used for daily treatment of ED and BPH symptoms.

• Usage: Allows for better control of symptoms and sexual function on a daily basis.

• Benefits: Improved flexibility and spontaneity, with a good safety profile.

💊 Vidalista 10 mg

• Purpose: Standard on-demand treatment dose for erectile dysfunction.

• Usage: Taken 30 minutes to 1 hour before sexual activity, not more than once daily.

• Benefits: Provides effective improvement in erectile response with moderate duration of action (up to 36 hours).

• Side Effects: Possible headache, flushing, nasal congestion, dizziness.

💊 Vidalista 20 mg

• Purpose: Higher dose for patients who require stronger effect or did not respond adequately to 10 mg dose.

• Usage: Taken on demand, 30 minutes before sexual activity, once daily max.

• Benefits: Enhanced efficacy in difficult-to-treat ED cases.

• Side Effects: Slightly increased risk of common PDE5 inhibitor side effects.

Mechanism of Action

Tadalafil works by inhibiting the PDE5 enzyme in the smooth muscle of the penis, increasing cyclic GMP levels, leading to smooth muscle relaxation and increased blood flow into the corpora cavernosa, thus facilitating erection during sexual stimulation.

Pharmacokinetics

• Onset of action: 30 to 60 minutes

• Duration of action: Up to 36 hours ("weekend pill")

• Metabolism: Hepatic via CYP3A4

• Elimination half-life: Approximately 17.5 hours

Contraindications

• Use with nitrates or nitric oxide donors

• Severe cardiovascular disorders

• Hypersensitivity to tadalafil

• Severe hepatic or renal impairment (dose adjustment needed)

Common Side Effects

• Headache

• Flushing

• Nasal congestion

• Dyspepsia

• Back pain (more common with longer duration doses)

Storage

• Store below 30°C

• Keep in a dry place away from sunlight and moisture